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Description

Green Tea Extract epicatechin

 

Epicatechin is a flavonoid, a plant compound present in a variety of foods. Technically speaking, flavonoids are a specific subgroup of polyphenols. These are naturally occurring substances found in plants that are known for their potent antioxidant and anti-inflammatory properties. Epicatechin is found in particularly high concentrations in black grapes, cocoa, apples, raspberries, cherries, and green tea (Camellia sinensis).

The medicinal use of Epicatechin rich foods dates back to the ancient civilizations of Asia and Central America. For example, the Kuna Indians of Panama have long been known for their remarkably low rate of cardiovascular disease, which is believed to be linked to their high consumption of cocoa. Epicatechin containing foods have also been highly prized in traditional Chinese and Ayurvedic medicine for thousands of years.

More recent scientific investigation has not only demonstrated the diverse variety of health benefits associated with the consumption of Epicatechin, such as a reduced risk of cardiovascular disease and diabetes, but also benefits for performance, including increased muscle size and strength and enhanced nitric oxide production and blood flow. This has brought this previously little-known supplement to the attention of competitive athletes, bodybuilders and recreational exercisers engaged in demanding exercise.

 

Product Name	Epicatechin
CAS No	490-46-0
Latin name	Camellia sinensis L.
Appearance	Off white to light pink fine powder
Specifications	≥90%
Pakage	1kg/bag, 25kg/drum
Storage	Moisture-roof and avoid light, sealed storage.
Test Method	HPLC

Epicatechin Benefits

• Enhancing muscle growth
• Increasing muscular strength
• Inhibiting myostatin
• Increasing follistatin
• Increasing nitric oxide levels
• Increasing blood flow
• Enhancing mitochondria number and function
• Providing anti-ageing effects
• Improving physical performance
• Enhancing cardiovascular health
• Protecting against muscle mass loss
• Increasing fat metabolism
• Improving carbohydrate metabolism
• Enhancing cognitive function
• Providing anti-inflammatory effects

Can Epicatechin increase muscle growth and strength?

The process of building muscle is a complex one, and while the role of resistance training and the consumption the appropriate amounts of certain nutrients, particularly protein, are well documented, less well understood are many of the underlying physiological mechanisms responsible for muscle growth and how certain natural substances can have a positive influence on these mechanisms to maximise gains in muscle size and strength. In recent years, Epicatechin has received considerable interest from strength athletes due to the increasing number of studies demonstrating its ability to increase muscle (1,2,4,8,9).

Unlike protein supplementation, which increases the amino acids available for muscle protein synthesis and testosterone, which binds to androgen receptors in muscle cells to stimulate protein synthesis, Epicatechin helps to increase size and strength by reducing levels of myostatin and increasing follistatin. Myostatin is a myokine, a type of regulating protein released by muscles. Opposing myostatin is a myokine called follistatin. Unlike myostatin, which suppresses muscular growth, follistatin promotes muscle growth by binding to the myostatin receptor and inhibiting the function of myostatin.

Consequently, by shifting the balance between myostatin and follistatin in follistatin’s favour, we can stimulate greater muscle growth.

Gutierrez-Salmean et al., (1) investigated the effects of Epicatechin supplementation on myostatin and follistatin in human subjects. The study showed that as we age, levels of myostatin significantly increase (28%) while those of follistatin decrease (30%). This combination results in a loss of muscle mass over time. In the trial, participants were given 150mg of Epicatechin per day for 7 days. This resulted in a 49.2% increase in the ratio follistatin to myostatin, which was accompanied by a 7% increase in strength.

Mafi and colleagues (2) achieved similar results when they conducted a randomised control trial, considered to be the ‘gold standard’ in research, to investigate the effects of Epicatechin supplementation combined with 8 weeks of resistance training on muscle. The results showed that the combination of resistance training and Epicatechin produced a significant decrease in myostatin and an increase in follistatin, follistatin/myostatin ratio, leg press and chest press strength, and muscle mass in comparison to a placebo.

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