Smoke Tree Extract Fisetin suppliers Smoke Tree Extract Fisetin manufacturers Smoke Tree Extract Fisetin factory free sample

Smoke Tree Extract  Fisetin (FIS, 3,3′,4′,7-tetrahydroxyflavone), also known as fisetin, is a natural flavonoid compound extracted from plants such as the Anacardiaceae plant, Fisetin. Flavins have pharmacological properties such as antioxidant and anti-inflammatory properties.

Iquire Send an Inquiry



Smoke Tree Extract Fisetin Introduction

Fisetin (Smoke Tree Extract)- was is prepared from Cotinus coggygria Scop trunk, using suitable solvents such as water and alcoho, or mixtures of these solvents. The ratio of starting plant material to Extract is approximately 400:1. It contains NLT 98.0% of the labeled amount of Fisetin, calculated on the dried basis.

Fisetin (FIS, 3,3′,4′,7-tetrahydroxyflavone), also known as fisetin, is a natural flavonoid compound extracted from plants such as the Anacardiaceae plant, Fisetin. Flavins have pharmacological properties such as antioxidant and anti-inflammatory properties.

Product Name Smoke Tree Extract Fisetin
CAS No 528-48-3
Latin name Cotinus coggygria Scop.var.cinerea Engl.
Appearance yellow needle crystal powder
Specifications 10%,30%,50%,80%,98%
Pakage 1kg/bag, 25kg/drum
Storage Moisture-roof and avoid light, sealed storage.
Test Method HPLC

The function of Smoke Tree Extract Fisetin


Fisetin is a bioflavonoid antioxidant that can help maintain glutathione levels and mitochondrial function in the presence of oxidative stress. It has the potential to cross the blood-brain barrier, which may help maintain neuronal function.
Fisetin may support the body’s antioxidant arsenal through direct free radical scavenging activity and boosting glutathione levels. In vitro studies show that fisetin may support glutathione, a very active antioxidant naturally occurring in the body, by providing cysteine ​​(a building block of glutathione) to cells or enhancing glutathione synthesis. thione. Fisetin may help regulate the production of many proteins involved in protecting the body from oxidative stress and maintaining redox homeostasis (the balance between the rate of free radical production and the rate of scavenging of various antioxidants).


In recent years, the anti-tumor effect of fisetin has attracted people’s attention. Studies have shown that fisetin can exert anti-tumor effects by inducing tumor cell apoptosis, affecting tumor cell signal transduction pathways, inhibiting tumor cell proliferation, and inhibiting tumor cell migration and invasion.
Fisetin mainly induces tumor cell apoptosis through activating Caspase, downregulating BIRC8 and Bcl2L2, and inhibiting COX-2.
The natural product fisetin can inhibit the growth and spread of tumor cells through multiple pathways. At the same time, fisetin has the characteristics of being widely distributed in nature, having few toxic and side effects, and acting in multiple ways. It is believed that with the continuous deepening of the research on the anti-tumor mechanism of fisetin, it is expected to be used in clinical practice more scientifically and rationally, providing a basis for Human Health Career Services.

Anti-cancer effect

The researchers compounded drug carriers with Rhus extract containing fisetin, xanthophyllin, sulfaterin and rhodinin to obtain a composition with anti-cancer activity. Activity experiments showed that Rhus extract has anti-cancer properties in humans. cells, anti-uterine cancer cells, anti-human skin cancer cells and human colon cancer cells. Its main mechanism is to induce the organ differentiation of cancer cells into normal cells by transforming cancer cell genes.
Fisetin is the most typical active compound among Rhus flavonoid compounds, which can effectively inhibit the proliferation of prostate cancer cells and induce their apoptosis. In human lung cancer cells, fisetin can reduce the production of MMPs by inhibiting MAP kinase and NF-κB pathways. It also promotes the proliferation and apoptosis of breast cancer, cervical cancer, blood cancer and other cells. Therefore fisetin is considered to be an anticancer agent with development potential.


Mainly Specifications of Fisetin

Fisetin Powder 10% HPLC
Fisetin Powder 30% HPLC
Fisetin Powder 50% HPLC
Fisetin Powder 80% HPLC
Fisetin Powder 98% HPLC


Benefits of Fisetin

Fisetin is a super antioxidant and inflammation killer, effectively inhibiting the growth of Staphylococcus aureus.
Fisetin has great anti-tumor function,prevent tumor cells entering blood and inhibit the metastasis of tumor cells.
Fisetin has powerful ability to remove senescent cells, become a strong anti-aging ingredient.


Typical Specification Sheet of Fisetin 98%

Analysis Items Specifications Methods
HPTLC Sample exhibits major bands similar in position and color to standard solution.
HPLC Retention time of the sample matches with the standard in HPLC purity test.
Active Ingredients Tests
Fisetin ≥98.00% HPLC
Physical Tests
Appearance Light yellow fine powder Visual
Odor & taste Characteristic Organoleptic
Particle size 98% pass 80mesh Ch.P 2020 IV<0982>
Water ≤5.00% GB 5009.3
Residue on Ignition ≤5.00% GB 5009.4
Chemical Tests
Heavy Metals ≤10.00ppm GB 5009.74
Pb<Lead> ≤2.00ppm GB 5009.12
As<Arsenic> ≤2.00ppm GB 5009.11
Cd<Cadmium> ≤1.00ppm GB 5009.15
Hg<Total mercury> ≤0.10ppm GB 5009.17
Solvent Residues GB 5009.262 GB 5009.262
Pesticide residue GB 23200.113 GB 23200.113
Microbiological Tests
Total Bacterial Counts ≤1,000cfu/g GB 4789.2
Yeasts and Molds ≤100cfu/g GB 4789.15
E. Coli Negative in 1g GB 4789.38
Salmonella Negative in 10g GB 4789.4


Our Value-Added Rest Easy Service

>>>  Backvita has professional technicals can provide technical support documents like: Standards, Specs, COA, MOA, MSDS,Flow chart, Statements, Chromatograms, Nutritonal Facts, Stability test ,etc.

>>>  We promise to provide you with unique services to ensure you have no worries in product purchasing and selling.

>>>  Our global e-commerce data analyst team has 10 years of experience in the plant extract industry. They will provide you with data reports on the countries where your products are sold to help you make informed decisions. These data reports will include sales volume, sales channels, competitor analysis and other information to help you better understand market demand and trends, thereby optimizing your procurement and sales strategies.

>>>  In addition to data reports, we will also regularly provide you with information on market hot products and new products. This information will help you keep abreast of potential opportunities and trends in the market, and make adjustments and decisions based on market demands.

>>>  If you have your own exclusive brand, we will also provide you with promotional materials and posters to help you enhance your brand image and market awareness. Our design team will design exclusive promotional materials for your brand according to your needs and requirements. All these value-added services are provided free of charge to our partners’ customers.

>>>  Our goal is to focus on customers, provide you with worry-free services throughout the process, and help you achieve better performance and success.

>>>  If you have any questions or special needs about our value-added services, please feel free to contact us. We will do our best to help you and ensure your satisfaction. Thank you again for your support and attention to us, and we look forward to establishing a long-term cooperative relationship with you.


Contact Us


    Technology Support

    Basic Technical Support

    [ Technical Data Sheet]

    [Certificates Supplied]

    [Solvent Residues Report]

    [Third Party Certification]

    [Pesticide Residues Report]

    [Procession Information Sheet]

    [Nutritional Facts Information Sheet]

    [Microbiological Standards Test Report]

    Value-added technical support

    Packaging Shipping